Research Paper Volume 2, Issue 3 pp 133—159

A Two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways


Figure 3. GO enrichment clusters in xpa-1.. Genes that respond to oxidative stress and redox homeostasis are found in the enriched biological processes in xpa-1 vs. N2. Aging (p < 0.0007), regulation of carboxylic acid metabolism (p < 0.03), ER unfolded protein response (p < 0.05) and phosphate transport (p < 0.02). Genes in red and blue are found to be upregulated and downregulated, respectively.