Research Paper Volume 2, Issue 5 pp 285—297

Circadian clock proteins control adaptation to novel environment and memory formation


Figure 5. Exploratory activity of wild type and circadian mutant mice. (Upper panel) Locomotor and rearing activity measured in 5 min increments during 1 hr on day1 for wt (diamonds), Bmal1-/- (squares), Clock/Clock (triangles) and Cry1,2-/- (crosses) mice. Statistically significant difference with wt activity is shown as p values. Difference between wt, Clock/Clock and Cry1,2-/- locomotor activities, and between rearing activities of Bmal1-/- vs. Clock/Clock and wt vs. Cry1,2-/- is not statistically significant. (Lower panel) Cumulative traveled distance and rearing activity on days 1 and 2; For upper panels p values of statistically significant differences between wild type and circadian mutants are indicated. For lower panels * P<0.05.