Comparative transcriptional profiling identifies takeout as a gene
                        that regulates life span

Johannes Bauer; Michael Antosh; Chengyi Chang; Christoph Schorl; Santharam Kolli; Nicola Neretti; Stephen L. Helfand

doi:doi:10.18632/aging.100146

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Research Paper Volume 2, Issue 5 pp 298—310

Comparative transcriptional profiling identifies takeout as a gene that regulates life span

Figure 2. Comparison of genes upregulated and downregulated in DR, dSir2 overexpression and DN-Dmp53 expressing long-lived flies at Day 10. (A) Venn diagrams comparing upregulated and downregulated genes in DR, dSir2 overexpression, and DN-Dmp53 in a yw/w¹¹¹⁸ background at age 10 Days. Genes intersecting in all 3 sets are noted in box with arrow. (B) Heatmap comparing the average log2 fold changes for genes significantly altered in the yw/w¹¹¹⁸ DR with the equivalent genes in dSir2 and DN-Dmp53 expressing flies.