Research Paper Volume 2, Issue 5 pp 298—310

Comparative transcriptional profiling identifies takeout as a gene that regulates life span

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Figure 4. Overexpression of takeoutin either of three different adult tissues extends life span of males and females.(A) Expression of takeout in the adult nervous system using the ELAV-Switch neuronal specific GAL4 driver leads to ~25% increase in mean longevity. (B) Flies expressing takeout in the head fat body, S1-32 pericerebral fat body specific GAL4 driver, have ~20% extension of mean life span, while takeout expression in the abdominal fat body, S1-106 abdominal fat body specific GAL4 driver, (C) extends fly life span by ~12-18% (females: left panel; males: right panel; statistical analysis in Table 1 and 2; grey: controls; black: takeout).