Research Paper Volume 2, Issue 5 pp 298—310

Figure 5. Long-lived takeout overexpressing flies have increased expression of a subset of the upregulated genes found in DR, dSir2 overexpression and DN-Dmp53 expressing flies. Overexpression of takeout in adult neurons increases the expression of a subset of 9 genes from the 19 upregulated genes shared in yw/w¹¹¹⁸ DR, dSir2 overexpression and DN-Dmp53 expressing long-lived flies at Day 10. Fold change increase by qPCR of each of the noted genes using mRNA extracted from 10-Day old flies induced to express takeout (Elav-GeneSwitch-UAS-to) as compared to genetically identical controls Elav-GeneSwitch; UAS-to flies without fed diluent.