Research Paper Volume 2, Issue 9 pp 567—581

Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans

Figure 4. Klotho targets daf-2 gene activity and requires a functional daf-2/daf-16 genetic pathway for lifespan modulation.. See Figure 2 for legend and Table 2 for corresponding quantitative and statistical analysis.