Commentary Volume 2, Issue 10 pp 634—636
Is shortening of telomeres the missing link between aging and the Type 2 Diabetes epidemic?
Figure 1. Aging is a well-established risk factor for Type 2 Diabetes. Both insulin secretion and insulin sensitivity, the major pathogenetic processes in Type 2 Diabetes, become impaired with increasing age. Telomere shortening occurs with aging. Studies suggest that this process may be linked with impairments of both insulin secretion and insulin sensitivity.