Research Paper Volume 2, Issue 12 pp 959—968

Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells


Figure 3. Cisplatin induces the p-ΔNp63α and LKB1 protein levels in SCC cells. Wild type ΔNp63α cells and ΔNp63α-S385G cells were exposed to control media and 10μg/ml cisplatin for 24h. Protein levels were tested with indicated antibodies. Cytoplasmic (cyto) protein levels were tested with the anti-β-actin antibody. (A) No lactacystin treatment. (B) With lactacystin treatment.