Commentary Volume 3, Issue 1 pp 19—21

Figure 1. Hypothesis for spontaneous pregnancies after subcutaneous transplantation of ovarian tissues. Based on the work cited in this manuscript, we hypothesize that the transplanted healthy ovary provides the missing regenerative signals to peripheral niches and/or to the stromal niche in the remaining menopausal ovary that result in the resumption of neo-oogenesis.