Research Paper Volume 3, Issue 3 pp 223—236

Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice


Figure 7. Calorie restricted mediated alteration of survival signaling. This schematic diagram shows the contribution of three key down-regulated miRNAs in CR mice for up-regulation of Bcl-2, effecting the process of cell survival signaling through Caspases-9 and -3, resulting in a decline of apoptosis.