Research Paper Volume 3, Issue 3 pp 262—276

RasGrf1 deficiency delays aging in mice


Figure 1. Delayed Ageing in RasGrf1−/−.. (A) Survival curve of RasGrf1−/− male mice and of WT of the same genetic background. WT n = 47; RasGrf1−/− n = 45. Report the Kaplan - Meyer representation of the two groups (p<0.05). (B) Percentage of mice alive after a hundred and thirty weeks (*p<0.02) and a hundred and forty-seven weeks (**p<0.005) of the two cohorts. Maximal lifespan in wild type was a hundred and forty-seven weeks. Thus 20% of all the RasGrf1−/− cohort survived longer than the maximal lifespan of the wild types.