Research Paper Volume 3, Issue 3 pp 277—290

The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice

class="figure-viewer-img"

Figure 10. Correlation between p38 and PKCδ kinase levels and DNA damage and senescence in MEFs. (A) Scanning analyses of Western blots, expressed as ratio of p38 signal to β-tubulin signal. Bars represent SEM. (B) Correlation between the p38 kinase level and DNA damage in the different MEFs. The Pearson's correlation coefficient is indicated. (C) Scanning analyses of Western blots, expressed as ratio of PKCδ signal to β-tubulin signal. Bars represent SEM. (D) Correlation between the PKCδ level and the percentage of senescent MEFs in vitro from the different genotypes. The Pearson's correlation coefficient is indicated.