Research Paper Volume 3, Issue 3 pp 291—303

Lifespan extension and paraquat resistance in a ubiquinone-deficient Escherichia coli mutant depend on transcription factors ArcA and TdcA


Figure 6. Model for the regulation of lifespan and stress resistance by UbiG in E. coli.. The hypoxia-induced transcription factor ArcA contributes to the enhanced lifespan and paraquat resistance observed in the absence of ubiG in part by enhancing the expression of tdcA, a transcription factor involved in the metabolism of serine and threonine during anaerobic growth.