Research Perspective Volume 3, Issue 4 pp 450—454

Hyperactive when young, hypoactive and overweight when aged: Connecting the dots in the story about locomotor activity, body mass, and aging in Trpv1 knockout mice


Figure 2. Aged Trpv1−/− mice have a higher body mass (P = 1 × 10−3) and a lower general locomotor activity (P < 1 × 10−7) than their genetically unaltered littermates. Group means (± SE) and individual data are shown. The locomotor activity was measured by telemetry during a 3-h period at the beginning of the inactive phase. The ambient temperature was 28°C.