Research Perspective Volume 3, Issue 5 pp 548—554

Maternal diet, aging and diabetes meet at a chromatin loop


Figure 1. The role of maternal diet in the development-tal origins of metabolic disease. An abnormal diet during pregnancy can induce gene expression changes in the developing fetus. These changes are then perpetuated during many subsequent rounds of cell division throughout the lifetime of the offspring (cell memory) and may lead to an increased disease risk in the adulthood.