Research Paper Volume 3, Issue 6 pp 621—634

Store-Operated Ca2+ Entry (SOCE) Contributes to Normal Skeletal Muscle Contractility in young but not in aged skeletal muscle


Figure 4. Effects of Ni2+ on contractility of young diaphragm muscle. (A) Force vs. frequency relationship in control diaphragm muscles (open circles) or diaphragm muscles treated with NiCl2 (solid circles). (n = 3). (B) Intact diaphragm muscle bundles from young mice were electrically stimulated at 37°C with high frequency (200 Hz/min) in the absence (open circles, control) or in the presence of 3 mM NiCl2 (solid circles, NiCl2).