Research Paper Volume 3, Issue 6 pp 609—620

Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals


Figure 3. Levels of DNA damage and cell proliferation in spleen, thymus, liver, lung and kidney tissues of 7, 14, 24, 30 and 45 days old sham-irradiated and 1 Gy-irradiated male and female mice. Data are presented as a percentage of cells with more than 4 γH2AX foci per cell. Red bars represent the percentage of PCNA-positive cells that harbor more than 4 γH2AX foci per cell. CT-control, AC- acute effect, 30 minutes after exposure; DEL-delayed effect, 24 hours after exposure.