Research Paper Volume 3, Issue 6 pp 609—620

Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals


Figure 4. Radiation-induced DNA damage and cell proliferation in brain regions of male and female mice of different ages. Incidence of γ-H2AX foci in cerebellum, hippocampus, frontal cortex and olfactory bulb tissues of 7, 14, 24, 30 and 45 days old sham-irradiated and 1 Gy-irradiated male and female mice. Data are presented as average number of γH2AX foci per cell. CT-control, AC- acute effect, 30 minutes after exposure; DEL-delayed effect, 24 hours after exposure.