Research Paper Volume 3, Issue 9 pp 846—851

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease


Figure 1. An increased phosphorylation level of p150Glued in AD neurons. Hippocampal tissues of AD patients or age-matched controls were subjected to immunohistochemistry staining with phospho-specific antibodies against pS179-p150Glued. Plk1 phosphorylates p150Glued-S179 specifically [27].