Research Paper Volume 3, Issue 11 pp 1098—1109

Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor

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Figure 5. THC, but not C, extends life span in Drosophila under normal conditions. The effect of THC and RES (A) was analyzed in a yw background, and C (B) was analyzed in Oregon-R (WT) flies. Life span studies were carried out at 25°C with newly eclosed male (M) or female (F) flies for each longevity experiment (20 per vial; 4 vials were counted). Survivors were transferred to fresh vials containing THC, RES, or C (20—150 μM) every 2—3 days. The statistical analysis of the data is summarized in Table 1.