Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor

Lan Xiang; Yukiko Nakamura; Young-Mi Lim; Yasutoyo Yamasaki; Yumi Kurokawa-Nose; Wakako Maruyama; Toshihiko Osawa; Akira Matsuura; Noboru Motoyama; Leo Tsuda

doi:doi:10.18632/aging.100396

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Research Paper Volume 3, Issue 11 pp 1098—1109

Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor

Figure 6. THC and RES do not extend the life span of foxo or d4E-BP mutants. Effects of THC or RES (50 μM) on the life span of foxo−/− (A) or d4E-BP−/− (B) mutant Drosophila under natural conditions. Life span studies were carried out at 25°C with a total of around 80 newly eclosed male (M) flies (yw background). The statistical analysis of the data is summarized in Table 1.