Research Paper Volume 3, Issue 11 pp 1110—1119

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents


Figure 5. SkQ1 increases in dose-dependent manner the lifespan of female BALB/c mice if survival for the first 15% of deaths is considered. Three SkQ1 concentrations were used (nmol SkQ1/kg per day): (i) 1, (ii) 30, and (iii) 0.05 during the first 595 days and 140 for subsequent days. In B, p was <0.05 for 1 and 30 nmol SkQ1/kg per day compared with the control or 0.05/140 nmol SkQ1/kg per day. The vivarium used was the same as in Figure 4.