Research Paper Volume 4, Issue 6 pp 402—416

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice


Figure 3. Transcriptomic analyses on the hearts of mIGF-1 Tg versus WT mice. The hearts of 3 WT and 3 cardiac-restricted mIGF-1 Tg mice were excised and RNA was processed for Affymetrix Gene ChIP analyses. Data were analyzed using GeneSpring software. Represented genes are those showing fold changes (FC) starting from 1.3 and a p-value lower than 0.05.