Research Paper Volume 6, Issue 6 pp 481—495

Interaction between ROS dependent DNA damage, mitochondria and p38 MAPK underlies senescence of human adult stem cells


Figure 7. (A) Immunoblot analysis of p38 phosphorylation during 1 h H2O2 treatment. (B) SB had no effect on long-term p38 phosphorylation as detected by Western blot. (C) Selective inhibition of p38 activity abolished phosphorylation of MAPKAPK-2 during the whole observation period. Representative results of three independent experiments are shown. GAPDH was used as loading control.