Research Paper Volume 6, Issue 6 pp 481—495

Interaction between ROS dependent DNA damage, mitochondria and p38 MAPK underlies senescence of human adult stem cells


Figure 9. SB diminished ROS production and mitochondrial function in senescent hMESCs. (A) DCF, (B) DHR123, (C) Rho123, and (D) NAO fluorescence in control (Ctr), H2O2-treated and (SB+H2O2)-treated hMESCs at indicated time points as measured by flow cytometry (M ± SD, N = 3, *p<0.05, ***p<0.001, versus control, §p<0.05, §§§<0.001, versus H2O2-treated cells).