Research Paper Volume 6, Issue 8 pp 675—689

Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

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Figure 4. TR feeding does not affect daily rhythms in gene expression and behavior controlled by the circadian clock. (A and B) The expression of mRNAs of the circadian clock genes Per1 and Bmal1 in the liver (A) and in the spleen (B) of mice subjected to AL (black diamonds, solid black line) or TR (gray squares, gray line) feeding. (C) Daily in cage behavior of mice subjected to AL (black diamonds, solid black line) or TR (black triangles, dashed black line) feeding. 3 male mice per each time point and feeding regimen have been used. Data present Average +/− SEM; * − p<0.05, statistically significant difference between different treatments.