Research Paper Volume 6, Issue 12 pp 1094—1108

Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis

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Figure 6. Gene expression analysis of genes relevant to mitochondrial biogenesis in young and aged-iPSCs during neuronal differentiation in relation to the mitochondrial number. Normalized expression levels of mitochondrial genes superimposed to the curve obtained after interpolation of mitochondrial number during differentiation of y-iPSCs (A) and a-iPSCs (B).