Research Paper Volume 7, Issue 4 pp 256—268

High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice


Figure 1. Prolonged HFD-feeding leads to obesity and organ adiposity. (A) Experimental design. (B) Body weights of mice fed a LFD and HFD shown at the start and at 12, 24, 40 and 52 weeks after a HFD. (C) Mesenteric, (D) gonadal/epidydimal and (E) perirenal fat depots weights. (F) Liver weight measured upon sacrifice at 24, 40 and 52 weeks. Values shown are means ± SEM (n = 10-15 mice/group). Significance level set at p<0.05. *=significant from LFD at same time point, †=significant from same diet 24w, ‡=significant from same diet 40w.