Research Paper Volume 7, Issue 6 pp 383—388

High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males


Figure 1. High‐glucose diet regulates lifespan in a sex‐specific manner. (A) In hermaphrodites, high‐glucose diet (orange) reduced median and maximum lifespan compared to control (black). p < 0.0001 by log‐rank. (B) In males, high‐glucose diet increased median lifespan (p < 0.0001 by log‐rank) and had no effect on maximum lifespan. Median lifespans are indicated in parentheses. Composites of at least 3 replicates are shown. Individual experimental data are provided in Table S1.