Research Paper Volume 7, Issue 7 pp 475—485

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice


Figure 2. SkQ1 promotes granulation tissue formation and epithelization of old mice wound, but does not cause scar hypertrophy. H&E staining of transverse sections of the wounds of old mice at 7d (a) and at 13d (d); area of granulation tissue or scar is shown by the black dotted line. (b) Granulation tissue formation, and (c) epithelization of the wounds at 7d; (e) scar formation at 13d. Data are presented as mean ± SD; *P < 0.05 for SkQ1-treated versus control; ‡P < 0.05 for the untreated young versus old mice.