Research Paper Volume 7, Issue 7 pp 475—485

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice


Figure 4. Effect of SkQ1 on the cellular composition of the wound. (a) Representative micrographs of the H&E stained transverse sections at the edge of the wounds at 7d and 13d. (b) Edges of the wounds at 7d and 13d stained with antibodies against the macrophage marker F4/80. (c) Total cellular content, (d) infiltration of neutrophils and (e) macrophages (F4/80 positive cells) in granulation tissue at 7d and 13d. Data are presented as mean ± SD; *P < 0.05 for SkQ1-treated versus control; ‡P < 0.05 for the untreated young versus old mice.