Research Paper Volume 7, Issue 8 pp 568—578

Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females

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Figure 3. Correlations between epimutations and aging. (A) Exponential relation between age ranges and number of SEM. (B) Linear correlation between age ranges and log(SEM), red squares indicates mean log(SEM) value. (C) Linear correlation between age log(SEM) considering all samples independently. (D) Density plot describing age dependent shift in log(SEM).