Editorial Volume 7, Issue 10 pp 750—751

Cell death inhibition by KSHV


Figure 1. KSHV encodes a large repertoire of genes regulating survival of the infected cell in all stages of the viral life cycle. Genes identified by systematic transfection analyses to counteract cell death are given in red circles (ORF numbers are given). ORFs 22 and 25 may not enter the cell or may be trapped in the viral capsid in the early infection but are expressed in the infected cell and may be active in the lytic phase.