Research Paper Volume 7, Issue 12 pp 1171—1182

DNA repair in species with extreme lifespan differences


Figure 3. Pathway activation strength (PAS) for DNA repair signaling pathways. PAS values for DNA repair pathways in human vs. mouse and NMR vs. mouse (p < 0.05). Positive PAS values reflect upregulated signaling pathways in human or NMR compared with mouse, and negative values represent down-regulated pathways. PAS scores of zero indicate similarly acting pathways in mouse compared with human or NMR.