Research Paper Volume 7, Issue 12 pp 1212—1222

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and “early aging” mice


Figure 2. Survival proportions of irradiated C57Bl/6 female recipients. Four week-old female recipients were lethally irradiated with (1050 rads) and transplanted with 2 × 106 BM from 8 week-old (squares, n = 20) or 18 week-old (triangles, n = 17) male C57Bl/6 donors. Recipients of older (18 week-old) BM exhibited reduced longevity compared to recipients of younger (8 week) BM (p<0.001).