Research Paper Volume 7, Issue 12 pp 1185—1197

Knockout of Angiotensin AT2 receptors accelerates healing but impairs quality


Figure 1. Wound closure measurements in AT1R and AT2R transgenic mice show delayed AT1R−/− and accelerated AT2R−/− healing rate. (A) Representative images from WT, AT1R−/− and AT2R−/− mouse cohorts on day 5, 7 and 11 of wound healing. Plannimetric assessment of wound closure rate in AT1R−/− (B) and AT2R−/− (D). Complete wound closure of AT1R−/− (Panel C) and AT2R−/− (E) mice. Data are means ± SEM *p<0.05.