Research Paper Volume 8, Issue 2 pp 231—244

Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

Figure 4. Loss of filamentous structures in AZD8055-treated cells. Fibroblasts at CPD 73 exposed to 35 nM or 70 nM AZD8055 or equivalent volume of DMSO for 1 week were fixed and stained using sulforhodamine B, then imaged by phase contrast microscopy. Left panel imaged with X40 objective; right panel magnification of regions outlined by black boxes.