Research Paper Volume 8, Issue 2 pp 231—244

Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

Figure 5. AZD8055 treatment reverses stress fiber formation in near-senescent cells. Late CPD HF043 fibroblasts were exposed to (A) DMSO vehicle control or (B) AZD8055 for 7 days then fixed and stained for actin using FITC-phalloidin. Imaging was carried out using a Zeiss AxioSkop II with x100 oil immersion lens. Representative images are shown for each treatment condition.