Research Paper Volume 8, Issue 1 pp 178—191

Ghrelin receptor regulates adipose tissue inflammation in aging

Figure 2. GHS-R ablation suppresses age-associated increase of expression of pro-inflammatory cytokines in WAT. Young (4-5 months) and old (13-16 months) mice were used. Expression of F4/80 (A), MCP1 (B), TNF-α (C), IL-1β (D), IL-6 (E), CD11c (F), CD206 (G), and CD301 (H) genes in epididymal WAT from young and old WT and Ghsr−/− mice. N = 6. #p<0.05, ##p<0.001, old vs. young WT; *p<0.05, **p<0.001, WT vs. Ghsr−/−.