Research Paper Volume 8, Issue 4 pp 642—661

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways

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Figure 1. Log Fold change of differentially expressed genes in at least one treatment relative to 12 hour ad libitum feeding (12AL). Blue indicates down-regulation and red upregulation relative to 12AL. 10CR, 20CR, 30CR and 40CR refer to 10 %, 20 %, 30 % and 40 % restriction and 24AL to 24h ad libitum feeding.