Research Paper Volume 8, Issue 4 pp 642—661

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways


Figure 1. Log Fold change of differentially expressed genes in at least one treatment relative to 12 hour ad libitum feeding (12AL). Blue indicates down-regulation and red upregulation relative to 12AL. 10CR, 20CR, 30CR and 40CR refer to 10 %, 20 %, 30 % and 40 % restriction and 24AL to 24h ad libitum feeding.