Research Paper Volume 8, Issue 3 pp 441—454
Altered lipid metabolism in the aging kidney identified by three layered omic analysis
Figure 4. Lipidome analysis shows age-specific clustering and a decrease of lipid species and subspecies with age. (a) Hierarchical clustering of lipid subspecies detected in all organ samples. Low abundant lipids are depicted in blue, high abundant lipids in red color. (b) Overall lipid sums detected in whole kidney lysates. C: Ceramide, PC: Phosphatidylcholine, PE: Phosphatidylehtanolamine, PG: Phosphatidylglycerol, PS: Phosphatidylserine, SM: Sphingomyeline (c) PE subspecies with significantly different abundance between age groups. (d) PC subspecies with significantly different abundance between age groups. (e) PS subspecies with significantly different abundance between age groups. (f) Cer subspecies with significantly different abundance between age groups. (g) SM subspecies with significantly different abundance between age groups. Boxplots depict mean values with whiskers showing 5-95% percentile. **p<0.01; ***p<0.001.