Figure 2. Results of Elevated Plus Maze (EPM) in female mice aged 2 and 8 months (Wt and 5XFAD). Time spent in open arms (A), Time spent in center maze (B), Locomotor activity (C), Rears/vertical activity (D), Representative track sheets showing duration dependent changes in time spent in and number of entries on the open arm and closed arm in EPM (E). Data represented as observed mean ± Standard Error of the Mean (SEM); (n = 10 for each group). *p<0.05; **p<0.01; ****p<0.0001.