Research Paper Volume 8, Issue 4 pp 664—684

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice


Figure 4. β-amyloid pathway gene expression in in female mice aged 2 and 8 months (Wt and 5XFAD) for Bace1 (A), Amyloid Beta (A4) precursor (B) and representative Western blot for BACE1 (C), sAPP (D) and p-Tau (Ser 396) /Tau ratio quantifications (E). Bars represent mean ± Standard Error of the Mean (SEM), and values are adjusted to 100% for levels Wt at 2 months. **p<0.05; **p<0.01; ***p<0.001.