Research Paper Volume 8, Issue 4 pp 664—684

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice


Figure 5. Oxidative stress and pro-inflammatory markers in female mice aged 2 and 8 months (Wt and 5XFAD), representative Western blot for SOD1 (A), 4-HNE (B), representative gene expression for Aldh2 (C), iNOS (D), TNF-α (E), and IL-6 (F). Mean ± Standard Error of the Mean (SEM) from five independent experiments performed in triplicate are represented. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.