Research Paper Volume 8, Issue 4 pp 664—684

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice

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Figure 9. Gene expression for Jarid1a (A), G9a (B), Hdac1 (C), Hdac2 (D), Sirt1 (E), Sirt2 (F), and Sirt6 (G) in female mice aged 2 and 8 months (Wt and 5XFAD). Gene expression levels were determined by real-time PCR. Mean ± Standard Error of the Mean (SEM) from five independent experiments performed in triplicate are represented. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.