Research Paper Volume 8, Issue 4 pp 664—684

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice


Figure 9. Gene expression for Jarid1a (A), G9a (B), Hdac1 (C), Hdac2 (D), Sirt1 (E), Sirt2 (F), and Sirt6 (G) in female mice aged 2 and 8 months (Wt and 5XFAD). Gene expression levels were determined by real-time PCR. Mean ± Standard Error of the Mean (SEM) from five independent experiments performed in triplicate are represented. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.