Research Paper Volume 8, Issue 3 pp 521—533

Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid

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Figure 2. BS-I reduced amyloid plaque formation in APP/PS1 mice. (A) Images of ThioS-stained amyloid plaques in the hippocampus. (B) Statistics of ThioS-stained amyloid plaques in the hippocampus. APP/PS1/Vehicle group (Tg/Vehicle) compared with the wild-type control group (WT/Control), ** p < 0.01; BS-I treated groups compared with Tg/Vehicle group, ## p < 0.01. Error bars denote mean standard error of the mean (SEM), n = 3. Scale bar, 100 μM.