Research Paper Volume 8, Issue 3 pp 521—533

Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid


Figure 5. The PPI network of the effect of BS-I on AD. The network was constructed by mapping the most enriched functional genes to the PPI network constructed by the differentially expressed genes identified by the DNA microarray and differentially expressed proteins identified by the 2-DE. Immune genes are colored in blue and phagocytosis genes are colored in yellow. Multi-functional genes are identified by multiple colors. The size of a node depends on the number of pathways the gene is involved in. Grey nodes are non-target proteins that link the targets.