Research Paper Volume 8, Issue 4 pp 697—708

Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus – an aging connection

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Figure 1. Number of up- and downregulated genes in the prefrontal cortex and hippocampus of male and female animals exposed to MMC or CPP. (A) number of differentially expressed genes in PFC of animals in response to MMC; (B) number of differentially expressed genes in hippocampus of animals in response to MMC; (C) number of differentially expressed genes in hippocampus of animals in response to CPP.