N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice

Dalian Ding; Haiyan Jiang; Guang-Di Chen; Chantal Longo-Guess; Vijaya Prakash Krishnan Muthaiah; Cong Tian; Adam Sheppard; Richard Salvi; Kenneth R. Johnson

doi:doi:10.18632/aging.100927

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Research Paper Volume 8, Issue 4 pp 730—750

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice

Figure 6. CM potential normal in 6-month-old dwg/dwg mice. Mean (+/−SEM, n shown in panel) cochlear microphonic (CM) amplitude-intensity functions from 6-month-old +/+, +/dwg and dwg/dwg mice at 12, 16, 24 and 35 kHz. CM amplitudes increase with level and values plateau around 80 dB SPL.