Research Paper Volume 8, Issue 7 pp 1398—1415

Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk

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Figure 3. Predicted trajectories for men and women based on parameter estimates from the two-slope model of leukocyte telomere length (LTL) including sex and genetic risk score (GRS) effects. Male sex and addition of risk alleles in the GRS each result in shorter LTL. A decline after the centering age of 69.3 years is apparent for both men and women. Age in years is on the x-axis, and the plate-adjusted residuals of LTL re-scaled back to T/S-ratio is on the y-axis. The dashed line indicates centering age and the left corner panel is a zoomed version.